What is the drug interaction between digoxin and furosemide quizlet?

Patient taking diuretic, furosemide, and digoxin--which adverse effect is HCP concerned about?

Furosemide

Ototoxicity

Digoxin Toxicity

Hypoglycemia

Digoxin toxicity

Furosemide is loop diuretic and can cause hypokalemia, which increases risk for digoxin toxicity. Clients taking these 2 med should also take potassium supplements.
Furosemide can cause ototoxicity and hyperglycemia

Digoxin is effective in treating heart failure due to which pharmacological actions? (select all that apply)

Exerts positive inotropic action

Decreases cardiac output

Decreases sympathetic tone

Increases vascular constriction

Increases myocardial contractility

Exerts positive inotropic action

Decreases sympathetic tone

Increases myocardial contractility

Client starts drug therapy, but next day reports palpitation. HCP orders lidocaine 50 mg IV bolus. Client should be monitored for which adverse reaction to lidocaine?

Metabolic alkalosis

Hypertension

Tachycardia

Paresthesia

Paresthesis

High doses of lidocaine can lead to numbness and even seizures.
High doses can also cause hypotension and bradycardia.

HCP prescribes captopril to tx client's hypertension and also alleviate his heart failure. Client should avoid which OTC?

ibuprofen

acetaminophen

calcium carbonate

diphenhydramine

Ibuprofen

Taking an NSAID with an ACE inhibitor reduces an ACE inhibitor's effectiveness.
Food also decreases absorption of captopril.

HCP prescribes quinidine gluconate as an oral antidysrhythmic agent. Nurse should question use of quinidine for client taking Digoxin due to a possible drug interaction that can result in which adverse effect?

Liver toxicity

Quinidine toxicity

Digoxin toxicity

Cardiotoxicity

Digoxin toxicity

Quinidine may double digoxin levels by reducing the elimination of digoxin.
Can also cause liver dysfunction, and severe cardiotoxicity--but these are not due to digoxin interaction.

Client taking bumetanide and spironolactone. Using these drugs together may reduce the risk of which adverse effect?

Hypokalemia

Hyponatremia

Hyperglycemia

Hypochloremia

Hypokalemia

Spironolactone is potassium-sparing and causes the retention of potassium. This reduced risk of hypokalemia from bumetanide (loop diuretic with potassium loss)

Client is taking HCTZ for hypertension. To monitor for adverse effects of this drug, you monitor for which? (select all that apply)

Ototoxicity

Hyponatremia

Hypokalemia

Dehydration

Hypoglycemia

Hyponatremia
Hypokalemia
Dehydration

Client is taking losartan for hypertension. She asks about stopping contraception and starting a family. You inform her that losartan is unsafe to take during pregnancy due to which risk?

Macrosomia

Fetal injury

Gestational diabetes

Thromboembolic disease

Fetal injury

Client is about to start taking aliskiren to treat hypertension. Which of the following should you tell the client to avoid to ensure optimal absorption of this drug?

Soy sauce

Green, leafy vegetables

Fatty foods

Foods high in carbohydrates

Fatty foods

Fatty foods reduce absorption of aliskiren (Direct Renin Inhibitor)

Aside:
Avoid soy sauce with MAOIs b/c it has tyramine

Green, leafy veggies can interfere with warfarin.

While instructing a client about using isosorbide to treat angina, you advise the client to avoid which of the following?

Milk

Caffeine

Alcohol

Grapefruit juice

Alcohol

Alcohol increases hypotensive effects of isosorbide.

Aside:
Milk can interfere with iron supplements.

Caffeine can worsen adverse effects of beta 2 adrenergic agonists. (albuterol)

Grapefruit juice can interfere with many drugs, including calcium channel blockers.

Sodium channel blocker that treats supraventricular and ventricular dysrhythmias

Quinidine

Potassium channel blocker that treats ventricular fibrillation and ventricular tachycardia

Amiodarone

Calcium channel blocker that treats supraventricular tachycardia and atrial fibrillation or flutter

Verapamil

Beta adrenergic blocker that controls atrial and ventricular tachycardia

Propranolol

You are caring for a client taking oral amiodarone to treat atrial fibrillation. You advise the client to watch and report which of the following? (select all that apply)

Cough

Blurred vision

Dizziness

Sore throat

Fever

Cough
Blurred vision
Dizziness
Fever

amiodarone is a potassium channel blocker--can cause pulmonary toxicity (dyspnea, cough, fever, and chest pain). Can also cause corneal microdeposits, causing blurred vision and photophobia. Also dizziness and ataxia. Unlikely to cause sore throat, but can cause dry cough.

Client's atrial dysrhythmia fails to respond to other antidysrhythmia therapies. You anticipate the HCP might try which drugs whose off-label use includes refractory atrial dysrhythmias?

Propranolol

Lidocaine

Flecainide

Amiodarone

Flecainide

is a sodium channel blocker that treats serious ventricular dysrhythmias

Aside:
Propranolol (beta adrenergic blocker) useful with exercise induced dysrhythmias.
Lidocaine (sodium channel blocker) treats ventricular dysrhythmias.
Amiodarone (potassium channel blocker) treats recurrent ventricular fibrillation and ventricular tachycardia.

What is the drug interaction between digoxin and furosemide?

Furosemide and digoxin are often used together but may require more frequent evaluation of your digoxin, potassium, and magnesium levels. You should notify your doctor if you have symptoms, such as weakness, tiredness, muscle pains or cramps, nausea, decrease appetite, visual problems, or irregular heartbeats.

Which medication can interfere with absorption of digoxin?

Drugs which reduce digoxin absorption include the antacids aluminium hydroxide, magnesium hydroxide and magnesium trisilicate, the antidiarrhoeals kaolin and pectin, the hypocholesterolaemic agent cholestyramine and the chemotoxins cyclophosphamide, vincristine and bleomycin.

Which medication increases the likelihood of digitalis toxicity quizlet?

You are more likely to have this condition if you take digoxin, digitoxin, or other digitalis medicines along with drugs that interact with it. Some of these drugs are quinidine, flecainide, verapamil, and amiodarone. If your kidneys do not work well, digitalis can build up in your body.

When teaching a client about digoxin which symptom will the nurse include?

Signs and symptoms of digoxin toxicity are bradycardia (heart rate less than 60), nausea, vomiting, visual changes (halos), and arrhythmias.